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Product Name: Misoprostol
Generic Name: Misoprostol
Common Brands: Cytotec
Pharmaceutical Categories: Gastrointestinal, Digestive Health, Women's Health
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Misoprostol (trade names include Cytotec, Apo-Misoprostol, Cytolog, Misoprost, Gymiso, Misotrol) is a medication from prostaglandin E1 (PGE1) analogues pharmacological group. This medicine is prescribed to prevent development of stomach ulcers, which may sometimes be caused by arthritis medications that are called non-steroidal anti-inflammatory drugs (NSAIDs). It works by reducing the amount of acid released by the stomach and protecting the stomach lining, which helps to reduce the risk of stomach ulcers. Misoprostol is indicated to treat acute ulcers in the stomach (gastric ulcers), or in the first part of the small intestine (duodenal ulcers) and to prevent bleeding in the stomach or upper intestine in hospital patients after surgery.
Cytotec (Misoprostol) is also commonly used for labor induction (the process or treatment that stimulates childbirth and delivery), myomectomy, medical abortions (as an alternative to surgical abortion), early pregnancy loss, postpartum bleeding (postpartum hemorrhage, PPH), cervical ripening, trigeminal neuralgia, insertion of intrauterine contraceptive device. Medical abortion (induction of labour) has the advantage of being cheaper, simpler, less invasive, not requiring anesthesia, and not having the risk of scarring and adhesions associated with surgical abortion. Thats why misoprostol is also called as "abortion pills".
Customers also buy these medications from the same pharmacological classes:
Carboprost (Hemabate, Prostodin)
Clomiphene (Clomid)
Dinoprost (Enzaprost-F, Prostin-F2 Alpha)
Dinoprostone (Propess, Prostin-E2)
Domperidone (Motilium)
Enprostil (Fundyl)
Esomeprazole (Nexium)
Gemeprost (Cervagem, Cervidil)
Mifepristone (Mifeprex)
Omeprazole (Prilosec)
Oxytocin (Pitocin, Syntocinon)
Pantoprazole (Protonix)
Rabeprazole (Aciphex)
Ranitidine (Zantac)
Sulprostone (Nalador)
Pharmaceutical and medical classifications:
Abortion pills
Antacids, antireflux agents and antiulcerants
Drugs acting on the uterus
Medications for medical abortion
Preparations for the treatment of peptic ulcer
Prostaglandins and their analogs
Start labor drugs
Women's health products
The Anatomical Therapeutic Chemical (ATC) classification system (developed by the World Health Organization):
A - Alimentary tract and metabolism
A02 - Drugs for acid related disorders
A02B - Drugs for peptic ulcer and gastro-oesophageal reflux disease (GORD)
A02BB - Prostaglandins
A02BB01 - Misoprostol
G - Genito urinary system and sex hormones
G02 - Other gynecologicals
G02A - Uterotonics
G02AD - Prostaglandins
G02AD06 - Misoprostol
Medical conditions for misoprostol in the International Statistical Classification of Diseases and Related Health Problems:
Disorders of trigeminal nerve - G50
Trigeminal neuralgia - G50.0
Gastric ulcer - K25
Duodenal ulcer - K26
Peptic ulcer, site unspecified - K27
Other diseases of stomach and duodenum - K31
Spontaneous abortion - O03
Complete or unspecified spontaneous abortion without complication - O03.9
Medical abortion - O04
Other abortion - O05
Unspecified abortion - O06
Failed attempted abortion - O07
Maternal care for abnormality of pelvic organs - O34
Maternal care due to uterine scar from other previous surgery - O34.29
Maternal care for cervical incompetence, first trimester - O34.31
Failed induction of labor - O61
Postpartum hemorrhage - O72
Encounter for contraceptive management - Z30
Encounter for insertion of intrauterine contraceptive device - Z30.430
Other postprocedural states - Z98
History of uterine scar from previous surgery - Z98.891
Pregnancy category:
X - Australia
X - United States (Should not be used during pregnancy)
Forms of active pharmaceutical ingredients (APIs):
Misoprostol Base
Chemical, international, and other names of this drug:
Methyl (+-)-11-alpha,16-dihydroxy-16-methyl-9-oxoprost-13-en-1-oate
Misoprostole
Misoprostoli
Misoprostolo
Misoprostolum
Mizoprostol
Mysoprostol
Most known trade names (brands and generics) worldwide:
Alsoben - Unimed Pharmaceuticals, Hien Vi Pharmaceutical
Apo-Misoprostol - Apotex, Agencia Lei Va Hong, Hind Wing
Cyprostol - Pfizer
Cytolog - Zydus Cadila
Cytotec - Pfizer, Continental Pharma, GD Searle, NPIL Pharmaceuticals, Perrigo, Primal Chemical, The Glory Medicina, Zuellig Pharma
Gastrul - Fahrenheit
GyMiso - HRA Pharma, Linepharma International
Kontrac - Fourrts India Laboratories
Misodex - Sefarma
Misoprost - Cipla
Misoprostol - IVAX, Pro Doc, Stada
Misotrol - Sanofi
Mizoprostol - Beijing Zizhu Pharmaceutical
Noprostol - Novell Pharmaceutical Laboratories
Prestakind - Mankind Pharma
Zitotec - Sun Pharmaceutical Industries
Other medicines used in combinations with misoprostol:
Diclofenac
Methotrexate
Mifepristone
Naproxen
References and external sources:
Misoprostol main article on Wikipedia: https://en.wikipedia.org/wiki/Misoprostol
Misoprostol compound on PubChem: https://pubchem.ncbi.nlm.nih.gov/compound/Misoprostol
Misoprostol medicine on DrugBank: https://go.drugbank.com/drugs/DB00929
Misoprostol FAQ on MedlinePlus (revised 11/15/2017): https://medlineplus.gov/druginfo/meds/a689009.html
Ending pregnancy with medicines article on MedlinePlus (revised 04/15/2023): https://medlineplus.gov/ency/patientinstructions/000835.htm
Medical abortion on MedlinePlus: https://medlineplus.gov/ency/article/007382.htm
Cytotec (Misoprostol) tablets drug label on DailyMed (revised April 1, 2010): https://dailymed.nlm.nih.gov/dailymed/drugInfo...
Apotheca Misoprostol tablets drug label on DailyMed (revised February 1, 2017): https://dailymed.nlm.nih.gov/dailymed/drugInfo...
Cytotec (Misoprostol) 100 mcg and 200 mcg tablets official prescribing and patient information from the U.S. FDA (revised 07/10/2015): https://www.accessdata.fda.gov/drugsatfda_docs/label...
Cytotec (Misoprostol) 100 mcg and 200 mcg tablets prescribing and patient information from Pfizer (revised February 2021): https://labeling.pfizer.com/ShowLabeling.aspx?id=559
Apo-Misoprostol tablets information for the patient (medication guide) from Apotex pharmaceutical company: https://www.aapharma.ca/downloads/en/PIL/0138_PIL.pdf
GyMiso (Misoprostol) tablets consumer medicine information (CMI) leaflet from NPS MedicineWise (revised August 2013): https://www.nps.org.au/assets/medicines/...
Cytotec 200 microgram tablets Misoprostol package information leaflet for users on Medicines.org.uk (revised 10/2020): https://www.medicines.org.uk/emc/files/pil.1642.pdf
Revised: March 2024
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