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Product Name: Carbidopa, Levodopa
Generic Name: Carbidopa, Levodopa
Common Brands: Sinemet
Pharmaceutical Categories: Alzheimer's disease, Parkinson's disease
Where to buy Carbidopa, Levodopa online:
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Carbidopa with Levodopa (trade names include Sinemet, Apo-Levocarb, Co-Careldopa, Sinemet CR, Dopadura C, Dopicar, Sinemet LP, Duodopa, Duopa, Half Sinemet, Kardopal, Levocarb, Sinemet Plus, Levodopa Comp., Syndopa, Levomed, Nacom, Nakom, Rytary, Sinemet Retard, Syndopa CR, Tidomet) is a combined antiparkinson drug from dopa derivatives and decarboxylase inhibitors pharmacological groups. This medication is used for the treatment of Parkinson's disease, its symptoms and conditions, including postencephalitic parkinsonism, idiopathic Parkinson's disease, symptomatic parkinsonism, muscle stiffness, tremors, spasms, poor muscle control; to treat Parkinson symptoms caused by carbon monoxide poisoning or manganese intoxication. It is also indicated for the therapy of dopamine-responsive dystonia (DRD), periodic limb movement disorder, restless legs syndrome (RLS), amblyopia.
Symptoms of Parkinson's disease may be caused by low levels of chemical called dopamine in the brain. Levodopa works by converting to dopamine in the brain. Carbidopa helps prevent the breakdown of levodopa before it can reach the brain and take effect.
Customers also buy these medications from the same pharmacological classes:
Amantadine (Symmetrel)
Bromocriptine (Parlodel)
Cabergoline (Dostinex)
Carbidopa, Entacapone, Levodopa (Stalevo)
Dihydroergocryptine (Almirid)
Donepezil (Aricept)
Foscarbidopa, Foslevodopa (Vyalev)
Galantamine (Reminyl)
Lisuride (Dopergin)
Melevodopa (Levomet)
Memantine (Namenda)
Pergolide (Permax, Prascend)
Piribedil (Trivastal)
Pramipexole (Mirapex)
Procyclidine (Kemadrin)
Rivastigmine (Exelon)
Ropinirole (Requip)
Rotigotine (Neupro)
Selegiline (Eldepryl)
Trihexyphenidyl (Artane)
Pharmaceutical and medical classifications:
Antiparkinsonian drugs
Dopamine precursors
Central nervous system agents
Combinations of dopa derivatives with decarboxylase inhibitors
Combined medications for the treatment of Parkinson's disease
Dopamine agonists with decarboxylase inhibitors
Dopaminergic antiparkinsonism agents
Medicines to treat parkinsonism
Muscle relaxants
The Anatomical Therapeutic Chemical (ATC) classification system (developed by the World Health Organization):
N - Nervous system
N04 - Anti-parkinson drugs
N04B - Dopaminergic agents
N04BA - Dopa and dopa derivatives
N04BA02 - levodopa and decarboxylase inhibitor
Medical conditions for carbidopa with levodopa in the International Statistical Classification of Diseases and Related Health Problems:
Parkinson's disease - G20
Parkinsonism, unspecified - G20.C
Secondary parkinsonism - G21
Postencephalitic parkinsonism - G21.3
Parkinsonism in diseases classified elsewhere - G22
Dystonia - G24
Other dystonia - G24.8
Other extrapyramidal and movement disorders - G25
Other specified extrapyramidal and movement disorders - G25.8
Restless legs syndrome - G25.81
Sleep disorders - G47
Sleep related movement disorders - G47.6
Periodic limb movement disorder - G47.61
Visual disturbances - H53
Amblyopia ex anopsia - H53.0
Other disorders of muscle - M62
Other specified disorders of muscle - M62.8
Muscle weakness (generalized) - M62.81
Muscle spasm - M62.83
Abnormal involuntary movements - R25
Tremor, unspecified - R25.1
Toxic effect of carbon monoxide - T58
Pregnancy category:
B3 - Australia
C - United States (Risk cannot be ruled out)
Forms of active pharmaceutical ingredients (APIs):
Carbidopa Base with Levodopa Base
Carbidopa Anhydrous with Levodopa Base
Carbidopa Monohydrate with Levodopa Base
Chemical, international, and other names of this drug:
Carbidopa/L-DOPA
Co-Careldopa
L-DOPA/Karbidopa
Karbidopa/Levodopa
Levocarb
Levodopa e Carbidopa
Levodopa en carbidopa
Levodopa et Carbidopa
Levodopa ja Carbidopa
Levodopa och Karbidopa
Levodopa og Carbidopa
Levodopa und Carbidopa
Levodopa y Carbidopa
Levodopa/Karbidopa
Lewodopa/Karbidopa
Most known trade names (brands and generics) worldwide:
Apo-Levocarb - Apotex
Atamet - Elan Pharmaceuticals
Carbidopa, Levodopa - Accord Healthcare, Actavis, Hexal, Mylan, Ratiopharm, Sandoz, Teva
Carbidopa, Levodopa CR - Sandoz
Carbilev - Ranbaxy, Aspen
Co-Careldopa - Teva
Credanil - Remedica, Goldplus Universal
Cronomet - Merck
Dopadura C - Merck
Dopicar - Teva, Merck
Duodopa - Solvay, Abbott, AbbVie, Neopharma, Wockhardt
Duopa - AbbVie
Half Sinemet - Bristol-Myers Squibb, United Drug
Kardopal - Orion Pharma
LCD - Intas Pharmaceuticals
Lebocar - Pfizer
Levocar - Sandoz
Levocarb - Teva, Biolab Sanus Farmaceutica
Levocarb CR - AA Pharma
Levocomp - Hexal
Levodopa Comp. - CT-Arzneimittel, Ratiopharm, Stada
Levomed - Medochemie, Komedic, Medline, Star Medical Supplies
Nacom - Bristol-Myers Squibb
Nakom - Sandoz, Lek, Merck
Nakom Mite - Sandoz
Parcopa - Schwarz Pharma
Parkidopa - Cristalia Produtos Quimicos Farmaceuticos
Parkinel - Bago Laboratorios
Rytary - Amneal Pharmaceuticals
Sinemet - Merck, Algorithm, Bristol-Myers Squibb, Chandra Bhagat Pharma, DKSH, Dr. Fisher Farma, DuPont, Eureco-Pharma, Euro Registratie, Four Star, Institute of Pharmaceutical Research and Technology, Invida, M & H Manufacturing, Medcor Pharmaceuticals, Menarini, Mylan, OBS Healthcare, Organon, Orifarm, P & D Pharmaceuticals, Ramco Pharm, United Drug, Vianex, Zuellig Pharma
Sinemet Plus - Merck, Bristol-Myers Squibb, Organon
Sinemet Retard - Merck, Bristol-Myers Squibb
Sinemet CR - Merck, Bristol-Myers Squibb, DKSH, Dr. Fisher Farma, Euro Registratie, Four Star, Institute of Pharmaceutical Research and Technology, Invida, Menarini, Mylan, Sofeco, Zuellig Pharma
Sinemet LP - Merck, Bristol-Myers Squibb
Syndopa - Sun Pharmaceutical Industries
Syndopa Plus - Sun Pharmaceutical Industries
Syndopa CR - Sun Pharmaceutical Industries
Tidomet - Torrent Pharmaceuticals, Kaspa Pharmaceutical Thailand, Metro Drug Distribution
Other medicines used in combinations with carbidopa and levodopa:
Entacapone
References and external sources:
Carbidopa/levodopa main article on Wikipedia: https://en.wikipedia.org/wiki/Carbidopa/levodopa
Carbidopa, Levodopa compound on PubChem: https://pubchem.ncbi.nlm.nih.gov/compound/441193
Levodopa and Carbidopa FAQ on MedlinePlus (revised 06/20/2024): https://medlineplus.gov/druginfo/meds/a601068.html
Sinemet (Carbidopa and Levodopa) tablets drug label on DailyMed (revised June 1, 2022): https://dailymed.nlm.nih.gov/dailymed/drugInfo...
Sinemet CR (Carbidopa and Levodopa) sustained-release tablets drug label on DailyMed (revised 12/2020): https://dailymed.nlm.nih.gov/dailymed/downloadpdffile...
Teva Carbidopa and Levodopa tablets drug label on DailyMed (revised May 3, 2024): https://dailymed.nlm.nih.gov/dailymed/drugInfo...
Sinemet (Carbidopa and Levodopa) tablets official prescribing information from the U.S. FDA (revised 03/2020): https://www.accessdata.fda.gov/drugsatfda_docs/label...
Sinemet CR (Carbidopa and Levodopa) sustained-release tablets official prescribing information from the U.S. FDA (revised 07/2014): https://www.accessdata.fda.gov/drugsatfda_docs/label...
Sinemet CR (Carbidopa and Levodopa) sustained-release tablets prescribing information from Merck pharmaceutical company (revised 04/2018): https://www.merck.com/product/usa/pi_circulars/...
Sinemet (Levodopa and Carbidopa) tablets 100 mg/25 mg, 250 mg/25 mg product monograph and consumer information from The Drug and Health Product Register (revised September 10, 2018): https://pdf.hres.ca/dpd_pm/00047333.PDF
Sinemet (Levodopa, Carbidopa) tablets consumer medicine information from NPS MedicineWise (revised November 2023): https://www.nps.org.au/assets/medicines/...
Sinemet (Carbidopa/Levodopa) 100 mg/25 mg, 250 mg/25 mg tablets and Sinemet Plus 25 mg/100 mg tablets package information leaflet for users from Medicines.org.uk (revised August 2023): https://www.medicines.org.uk/emc/files/pil.7805.pdf
Revised: January 2025
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