Product Name: Selegiline
Generic Name: Selegiline
Common Brands: Deprenyl, Eldepryl, Emsam
Pharmaceutical Categories: Alzheimer's Disease, Parkinson's Disease
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Selegiline or L-Deprenyl (trade names include Eldepryl, Emsam, Deprenyl, Anipryl, Egibren, Jumex, Jumexil, Moverdin, Selegos, Selgian, Selgin, Zelapar) is an antiparkinsonian drug from monoamine oxidase type B (MAO-B) inhibitors pharmacological group. This medication is used to treat symptoms of Parkinson's disease, parkinsonism, shaking palsy, paralysis agitans, such as dementia in Alzheimer's disease, shakiness (tremor), muscle stiffness, loss of normal movement, sudden switching between normal movement and stiffness, other movement disorders. This is a cognitive enhancing smart anti aging drug that improves brain functions, cognitive actions, concentration, the range of motion and ability to walk, dress, exercise. Selegiline works by increasing and extending the effects of levodopa, and helping to slow the progress of Parkinson's disease. Deprenyl is usually used in combination with other antiparkinson medications (e.g., levodopa, carbidopa).
Emsam (Selegiline in the form of transdermal patch) is prescribed for the therapy of depression and major depressive disorder.
This medication is also indicated to treat the symptoms of Cushing's disease and cognitive dysfunction in veterinary medicine for dogs, pets and animals.
Selegiline was tested and studied for the treatment of attention deficit hyperactivity disorder (ADHD); to stop smoking tobacco or cannabis.
Customers also buy these medications from the same pharmacological classes:
Carbidopa, Entacapone, Levodopa (Stalevo)
Carbidopa, Levodopa (Sinemet)
Dihydroergocryptine Mesylate (Almirid)
Pharmaceutical and medical classifications:
Anti aging drugs
Pharmaceutical drugs for the treatment of Parkinson's disease
Central nervous system agents
Dopaminergic antiparkinsonism agents
Meds to treat ADHD
Monoamine oxidase B (MAO-B) inhibitors
Stop smoking pills
Veterinary medications, pet meds
The Anatomical Therapeutic Chemical (ATC) classification system (developed by the World Health Organization):
N - Nervous system
N04 - Anti-parkinson drugs
N04B - Dopaminergic agents
N04BD - Monoamine oxidase B inhibitors
N04BD01 - Selegiline
Medical conditions for selegiline in the International Statistical Classification of Diseases and Related Health Problems:
Cushing's syndrome - E24
Dementia in Alzheimer's disease ( G30.-+ ) - F00*
Cannabis related disorders - F12
Major depressive disorder, single episode - F32
Major depressive disorder, recurrent - F33
Attention-deficit hyperactivity disorders - F90
Parkinson's disease - G20
Other specified degenerative diseases of nervous system - G31.8
Mild cognitive impairment, so stated - G31.84
Tobacco abuse counseling - Z71.6
B2 - Australia
C - United States (Risk cannot be ruled out)
Forms of active pharmaceutical ingredients (APIs):
Chemical, international, and other names of this drug:
Benzeneethanamine, N,alpha-dimethyl-N-2-propynyl-, (R)-
Most known trade names (brands and generics) worldwide:
Anipryl - Pfizer, Zoetis
Cognitive - Ebewe Pharma, Ever Pharma
Deprenyl - Orion Pharma, Sanofi-Aventis
Deprilan - Biosintetica Laboratorios
Egibren - Chiesi
Eldepryl - Orion Corporation, Allphar Services, Aspen, Asta Medica, Deprenyl Research, Douglas Pharmaceuticals, Draxis Health, Eisai, Ercopharm, Eumedica Pharmaceuticals, Genepharm, Mylan, Polyfarma, Reckitt Benckiser, Servipharm, Somerset Pharmaceuticals, Star Pharmaceuticals, Themis Medicare, Viatris
Emsam - Mylan, Bristol-Myers Squibb, Somerset Pharmaceuticals
Jumex - Sanofi-Aventis, Armstrong Laboratorios de Mexico, Chiesi, Chinoin Pharmaceutical and Chemical Works, Dexxon, DKSH, IDS Group, IVAX, Lexapharm, Metro Drug Distribution, Novartis, Paranova, The Glory Medicina, Torrent Pharmaceuticals, Zuellig Pharma
Jumexil - Farmalab Industrias Quimicas e Farmaceuticas
Moverdin - Kocak Farma Ilac
Niar - Abbott, Knoll
Otrasel - Cephalon, Lafon Laboratoires
Plurimen - Orion Pharma, Asta Medica, Viatris
Selegilin - AbZ-Pharma, Azupharma, CT-Arzneimittel, Mepha, Ratiopharm
Selegilina - Davur Laboratorios, Generis Farmaceutica
Selegiline - Alphapharm, Apotex, Biogaran, Generics UK, Mylan, Sandoz, Teva
Selegos - Medochemie, Britton Distributions, Derek Marketing, Komedic, Star Medical Supplies
Selerin - Cipla, Protec
Selgian - Ceva Animal Health, Biokema, Ceva Sante Animale, Sanofi-Aventis
Selgin - Intas Pharmaceuticals
Tonus - Acapi
Xilopar - Teva, Cephalon, Elan Pharmaceuticals, Esteve, Segix Italia
Zelapar - Teva, B & S Healthcare, Cardinal Health, Cephalon, Elan Pharmaceuticals, Lexon UK, Servipharm, Star Pharmaceuticals, Valeant Pharmaceuticals, Zeneus Pharma
References and external sources:
Selegiline main article on Wikipedia: https://en.wikipedia.org/wiki/Selegiline
D-Deprenyl article on Wikipedia: https://en.wikipedia.org/wiki/Selegiline
Selegiline compound on PubChem: https://pubchem.ncbi.nlm.nih.gov/compound/Selegiline
Selegiline Hydrochloride compound on PubChem: https://pubchem.ncbi.nlm.nih.gov/compound/Selegiline-hydrochloride
Selegiline medicine on DrugBank: https://www.drugbank.ca/drugs/DB01037
Selegiline Hydrochloride on DrugBank: https://www.drugbank.ca/salts/DBSALT000260
Selegiline FAQ on MedlinePlus (revised 01/15/2022): https://medlineplus.gov/druginfo/meds/a697046.html
Selegiline Transdermal Patch on MedlinePlus (revised 07/15/2018): https://medlineplus.gov/druginfo/meds/a607003.html
Apotex Selegiline Hydrochloride tablets drug label on DailyMed (revised November 28, 2018): https://dailymed.nlm.nih.gov/dailymed/lookup...
Zelapar (Selegiline Hydrochloride) orally disintegrating tablets drug label on DailyMed (revised June 1, 2021): https://dailymed.nlm.nih.gov/dailymed/drugInfo...
Emsam (Selegiline) patch drug label on DailyMed (revised May 15, 2020): https://dailymed.nlm.nih.gov/dailymed/drugInfo...
Eldepryl (Selegiline Hydrochloride) capsules official prescribing information from the U.S. FDA (issued January 2008): https://www.accessdata.fda.gov/drugsatfda_docs/label/...
EMSAM (Selegiline Transdermal System) official prescribing information from the U.S. FDA (issued June 2007): https://www.accessdata.fda.gov/drugsatfda_docs/label/...
Eldepryl (Selegiline Hydrochloride) 5 mg tablets product information from GP2U TeleHealth (revised 28 October 2010): https://gp2u.com.au/static/pdf/E/ELDEPRYL-PI.pdf
Eldepryl (Selegiline Hydrochloride) 5 mg and 10 mg tablets patient information leaflet from Medicines.org.uk (revised March 2021): https://www.medicines.org.uk/emc/files/pil.2251.pdf
Revised: May 2022
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