Product Name: Anastrozole
Generic Name: Anastrozole
Common Brands: Arimidex
Pharmaceutical Categories: Cancer, Women's Health
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Anastrozole (trade names include Arimidex, Anabrez, Anastrozol, Anastrozole Teva, Armotraz, Egistrozol, Ozolan, Sandoz Anastrozole, Trozolet) is an anticancer drug from aromatase inhibitors pharmacological group. This medicine is used for the treatment of hormone receptor-positive breast cancer in women who have been through menopause, including women with disease progression after tamoxifen therapy. It is also indicated to prevent breast cancer in postmenopausal women at high risk.
In combination with bicalutamide Arimidex is prescribed to treat peripheral precocious puberty, for instance due to familial male-limited precocious puberty (testotoxicosis) and McCune-Albright syndrome, in boys.
Anastrozole is in research and development studies for the treatment of gynecomastia, female infertility, endometriosis, endometrial cancer, androgen replacement therapy in men with hypogonadism, as a hormonal contraceptive in women with levonorgestrel vaginal ring.
This medication works by lowering the amount of the hormone estrogen in the body.
Customers also buy these medications from the same pharmacological classes:
Desogestrel, Ethinyl Estradiol (Desogen)
Estrogens conjugated (Premarin)
Levonorgestrel (Alesse, Amethia, Camrese)
Norethisterone (Aygestin, Norlutate)
Sildenafil Citrate (Female Viagra)
Tadalafil (Female Cialis)
Pharmaceutical and medical classifications:
Androgen replacement therapy meds
Medications for the treatments of breast cancer
Nonsteroidal aromatase inhibitors
The Anatomical Therapeutic Chemical (ATC) classification system (developed by the World Health Organization):
L - Antineoplastic and immunomodulating agents
L02 - Endocrine therapy
L02B - Hormone antagonists and related agents
L02BG - Aromatase inhibitors
L02BG03 - Anastrozole
Medical conditions for anastrozole in the International Statistical Classification of Diseases and Related Health Problems:
Malignant neoplasm of breast - C50
Malignant neoplasm of corpus uteri - C54
Malignant neoplasm of endometrium - C54.1
Testicular dysfunction - E29
Testicular hypofunction - E29.1
Disorders of puberty, not elsewhere classified - E30
Precocious puberty - E30.1
Hypertrophy of breast - N62
Endometriosis - N80
Female infertility - N97
Other osteochondrodysplasias - Q78
Polyostotic fibrous dysplasia - Q78.1
Encounter for contraceptive management - Z30
C - Australia
D - United States (Positive evidence of risk)
Forms of active pharmaceutical ingredients (APIs):
Chemical, international, and other names of this drug:
Most known trade names (brands and generics) worldwide:
Anabrest - Egis, Vifor Pharma
Anabrez - Sun Pharmaceutical Industries
Anadex - Medac
Anaromat - Actavis, Synthon
Anastralan - PharmaSwiss
Anastrozol - Actavis, Eurofarma Laboratorios, Mylan, Ratiopharm, Sandoz, Stada, Teva, Varifarma
Anastrozole - Accord Healthcare, Biogaran, Cipla, Fresenius, Generics UK, Mylan, Pro Doc, Ranbaxy, Sandoz, Teva
Anastrozolo - Actavis, DOC Generici, Mylan, Sandoz, Teva
Anatero - Lyka Labs, Hetero Healthcare
Anazole - Biomedis Oncology, United Laboratories
Apo-Anastrozole - Apotex
Apo-Nastrol - Apotex
Arimidex - AstraZeneca, ANI Pharmaceuticals, BB Farma, DKSH, Four Star, Medcor Pharmaceuticals, Mediwin Pharmaceuticals, NeoFarma Pharmaceuticals, Orifarm, Teva, Zuellig Pharma
Armotraz - Cipla, A.J. Mirza Pharma, Biosano Laboratorios, MS Farma
Egistrozol - Egis, Synthon
Femistra - Cadila Healthcare, Biogen, Zydus Cadila Healthcare
Mamostrol - Polpharma, Synthon
Mylan-Anastrozole - Mylan, Xixia
Ozolan - Glenmark Pharmaceuticals, Remedica
Sandoz Anastrozole - Sandoz
Teva-Anastrozole - Teva
Trozolet - Tecnofarma, Medicamenta Ecuatoriana
References and external sources:
Anastrozole main article on Wikipedia: https://en.wikipedia.org/wiki/Anastrozole
Anastrozole compound on PubChem: https://pubchem.ncbi.nlm.nih.gov/compound/Anastrozole
Anastrozole medicine on DrugBank: https://go.drugbank.com/drugs/DB01217
Anastrozole FAQ on MedlinePlus (revised 01/15/2018): https://medlineplus.gov/druginfo/meds/a696018.html
Hormone therapy for breast cancer FAQ on MedlinePlus (revised 09/24/2019): https://medlineplus.gov/ency/patientinstructions/000909.htm
Arimidex (Anastrozole) tablets drug label on DailyMed (revised April 26, 2021): https://dailymed.nlm.nih.gov/dailymed/drugInfo...
Anastrozole film-coated tablets drug label on DailyMed (revised May 13, 2020): https://dailymed.nlm.nih.gov/dailymed/drugInfo...
Anastrozole international trade names on Drugs.com: https://www.drugs.com/international/anastrozole.html
Arimidex (Anastrozole) tablets for oral use official prescribing and patient information from the U.S. FDA (revised 10/20/2010): https://www.accessdata.fda.gov/drugsatfda_docs/label/...
Arimidex (Anastrozole) 1 mg tablets product monograph from AstraZeneca pharmaceutical company (revised January 19, 2018): https://www.astrazeneca.ca/content/dam/az-ca/downloads/...
Arimidex (Anastrozole) 1 mg tablets official website: https://www.arimidex.com/
Armotraz (Anastrozole) 1 mg film-coated tablets prescribing information from Cipla pharmaceutical company (revised December 2017): https://www.ciplamed.com/content/armotraz-tablets
Anastrozole Sandoz tablets product information from NPS MedicineWise (revised 01 May 2018): https://www.nps.org.au/medicine-finder/anastrozole-sandoz-tablets
Arimidex (Anastrozole) 1 mg film-coated tablets package information leaflet from Medicines.org.uk (revised February 2020): https://www.medicines.org.uk/emc/files/pil.2199.pdf
Mylan Anastrozole 1 mg film-coated tablets package information leaflet from Medicines.org.uk (revised 11/2018): https://www.medicines.org.uk/emc/files/pil.2749.pdf
Revised: June 2021
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