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Product Name: Paroxetine
Generic Name: Paroxetine
Common Brands: Paxil
Pharmaceutical Categories: Antidepressants, Anti Anxiety
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Paroxetine (trade names include Paxil, Seroxat, Pexep, Paxil CR, Paroxetine Actavis, Pari CR, Aropax, Casbol, Deroxat, Seroxat CR, Eutimil, Paroxetine Biogaran, Frosinor, Mylan-Paroxetine, Oxetine, Paroksetiini GSK, Paroxetin Hexal, Paroxetine Sandoz, Paxtine, Rexetin, Paroxetine Teva, Serestill, Sereupin, Tagonis, Daparox, Divarius, Pexeva) is an antidepressant medication from selective serotonin reuptake inhibitors (SSRIs) pharmacological group. This medicine is indicated for the treatment of depression, certain types of anxiety, other nervous system disorders such as major depressive disorder, persistent depressive disorder, postpartum depression, obsessive-compulsive disorder, panic disorder, post-traumatic stress disorder, generalized anxiety disorder, social anxiety disorder, agoraphobia, alcoholism, alcohol use disorder, body dysmorphic disorder, borderline personality disorder, compulsive gambling, trichotillomania, dysautonomia, dysthymia, excoriation disorder, fibromyalgia, intermittent explosive disorder, somatoform pain disorder, vulvodynia, premature ejaculation, postmenopausal symptoms, premenstrual dysphoric disorder, hot flashes and night sweats due to menopause. It works by restoring the balance of serotonin, a natural substance in the brain, which helps to improve certain mood problems.
Customers also buy these medications from the same pharmacological classes:
Amitriptyline (Elavil)
Bupropion (Wellbutrin, Zyban)
Citalopram (Celexa)
Clomipramine (Anafranil)
Desvenlafaxine (Pristiq)
Doxepin (Sinequan)
Duloxetine (Cymbalta)
Escitalopram (Lexapro)
Etoperidone (Depraser)
Fluoxetine (Prozac)
Fluvoxamine (Luvox)
Imipramine (Tofranil)
Lamotrigine (Lamictal)
Nortriptyline (Aventyl, Pamelor)
Risperidone (Risperdal)
Sertraline (Zoloft)
Thioridazine (Mellaril)
Venlafaxine (Effexor)
Zimeldine (Zelmid)
Ziprasidone (Geodon)
Pharmaceutical and medical classifications:
Anti anxiety drugs
Antidepressants
Anxiolytics
SSRIs
The Anatomical Therapeutic Chemical (ATC) classification system (developed by the World Health Organization):
N - Nervous system
N06 - Psychoanaleptics
N06A - Antidepressants
N06AB - Selective serotonin reuptake inhibitors
N06AB05 - Paroxetine
Medical conditions for paroxetine in the International Statistical Classification of Diseases and Related Health Problems:
Alcohol related disorders - F10
Opioid related disorders - F11
Bipolar disorder - F31
Depressive episode - F32
Premenstrual dysphoric disorder - F32.81
Major depressive disorder, recurrent - F33
Persistent mood [affective] disorders - F34
Dysthymic disorder - F34.1
Phobic anxiety disorders - F40
Agoraphobia - F40.0
Social phobias - F40.1
Other anxiety disorders - F41
Panic disorder [episodic paroxysmal anxiety] - F41.0
Generalized anxiety disorder - F41.1
Obsessive-compulsive disorder - F42
Excoriation (skin-picking) disorder - F42.4
Reaction to severe stress, and adjustment disorders - F43
Post-traumatic stress disorder (PTSD) - F43.1
Somatoform disorders - F45
Body dysmorphic disorder - F45.22
Sexual dysfunction not due to a substance or known physiological condition - F52
Premature ejaculation - F52.4
Mental and behavioral disorders associated with the puerperium, not elsewhere classified - F53
Postpartum depression - F53.0
Specific personality disorders - F60
Borderline personality disorder - F60.3
Impulse disorders - F63
Pathological gambling - F63.0
Trichotillomania - F63.3
Intermittent explosive disorder - F63.81
Disorders of autonomic nervous system - G90
Familial dysautonomia [Riley-Day] - G90.1
Other and unspecified soft tissue disorders, not elsewhere classified - M79
Fibromyalgia - M79.7
Pain and other conditions associated with female genital organs and menstrual cycle - N94
Vulvodynia - N94.81
Menopausal and other perimenopausal disorders - N95
Menopausal and female climacteric states - N95.1
Pregnancy category:
D - Australia
D - United States (Positive evidence of risk)
Forms of active pharmaceutical ingredients (APIs):
Paroxetine Base
Paroxetine Hydrochloride
Paroxetine Hydrochloride Acetone Solvate
Paroxetine Hydrochloride Hemihydrate
Paroxetine Mesylate
Chemical, international, and other names of this drug:
Clorhidrato de Paroxetina
Paroksetiini
Paroksetin
Paroksetyna
Paroxetin
Paroxetina
Paroxetine HCl
Paroxetinum
Paroxetyne
Most known trade names (brands and generics) worldwide:
Apo-Paroxetine - Apotex
Aropax - Novartis, GlaxoSmithKline
Aropax CR - Novartis
Bectam - Labomed Instituto Farmaceutico
Casbol - Fournier
Cebrilin - Libbs Farmaceutica
Daparox - Angelini
Deroxat - GlaxoSmithKline
Divarius - Chiesi
Dom-Paroxetine - Dominion Pharmacal
Eutimil - GlaxoSmithKline
Extine - Arrow Pharmaceuticals
Frosinor - Novartis
Meplar - Baliarda Laboratorios
Mylan-Paroxetine - Mylan
Novo-Paroxetine - Novopharm
Optipar - GEA
Oxetine - Hexal
Paluxetil - Sandoz, Biochemie
Paradise XR - Torrent Pharmaceuticals
Pari CR - Ipca Laboratories
Parogen-CR - Gentech Healthcare
Paroksetiini - GlaxoSmithKline
Paronex - Sandoz
Parotin - Cipla
Paroxedura - Merck
Paroxetin - Actavis, Betapharm Arzneimittel, CT-Arzneimittel, GlaxoSmithKline, Hexal, Mepha, Ratiopharm, Sandoz, Stada, TAD Pharma
Paroxetine - Actavis, Alphapharm, Apotex, Arrow Generiques, Biogaran, Genpharm, GlaxoSmithKline, IVAX, Merck, Mylan, Pro Doc, Qualimed Pharma, Ranbaxy, Ratiopharm, Sandoz, Sanofi, Teva, Zydus Pharmaceuticals
Paxetil - Bial Laboratorios
Paxidep CR - Sun Pharmaceutical Industries
Paxil - GlaxoSmithKline
Paxil CR - GlaxoSmithKline
Paxtine - Alphapharm
Paxxet - Trima Pharmaceuticals, Unipharm
Petin-CR - Molekule India
Pexep - Intas Pharmaceuticals
Pexep CR - Intas Pharmaceuticals
Pexeva - JDS Pharmaceuticals, Norwich Pharmaceuticals, Noven Pharmaceuticals, Synthon
Pharmapar - Pharmascience
PMS-Paroxetine - Pharmascience
Posivyl - Chile Laboratorios
Psicoasten - Beta Laboratorios
Rexetin - Gedeon Richter
Sandoz Paroxetine - Sandoz
Serestill - Italfarmaco
Seretran - Drugtech Laboratorio, Recalcine Laboratorios
Sereupin - Abbott
Seroxat - GlaxoSmithKline, Novartis
Seroxat CR - GlaxoSmithKline, Firma Chun Cheong, Zuellig Pharma
Tagonis - GlaxoSmithKline, Janssen
Teva-Paroxetine - Teva
Tiarix - Casasco Laboratorios
Tiarix - Casasco Laboratorios
Traviata - Andromaco Laboratorios
Xerenex - Psicofarma Laboratorio
Xet CR - Zydus Cadila
Other medicines used in combinations with paroxetine:
Imipramine
Mirtazapine
Olanzapine
Tandospirone
References and external sources:
Paroxetine main article on Wikipedia: https://en.wikipedia.org/wiki/Paroxetine
Paroxetine compound on PubChem: https://pubchem.ncbi.nlm.nih.gov/compound/Paroxetine
Paroxetine Hydrochloride on PubChem: https://pubchem.ncbi.nlm.nih.gov/compound/Paroxetine-hydrochloride
Paroxetine medicine on DrugBank: https://go.drugbank.com/drugs/DB00715
Paroxetine Hydrochloride on DrugBank: https://go.drugbank.com/salts/DBSALT000132
Paroxetine FAQ on MedlinePlus (revised 01/15/2022): https://medlineplus.gov/druginfo/meds/a698032.html
Antidepressants FAQ on MedlinePlus: https://medlineplus.gov/antidepressants.html
Paxil (Paroxetine Hydrochloride) film-coated tablets and suspension drug label on DailyMed (revised January 18, 2023): https://dailymed.nlm.nih.gov/dailymed/drugInfo...
Paxil CR (Paroxetine Hydrochloride) extended release tablets drug label on DailyMed (revised January 10, 2024): https://dailymed.nlm.nih.gov/dailymed/drugInfo...
Zydus Paroxetine tablets film-coated drug label on DailyMed (revised September 28, 2023): https://dailymed.nlm.nih.gov/dailymed/drugInfo...
Paxil (Paroxetine Hydrochloride) tablets and oral suspension official prescribing information and medication guide from the U.S. FDA (revised 02/2021): https://www.accessdata.fda.gov/drugsatfda_docs/label...
Paxil CR (Paroxetine Hydrochloride) extended-release tablets for oral use official prescribing information and medication guide from the U.S. FDA (revised 09/2019): https://www.accessdata.fda.gov/drugsatfda_docs/label...
Paxil (Paroxetine Hydrochloride) tablets 10 mg, 20 mg, 30 mg product monograph and patient medication information from GlaxoSmithKline pharmaceutical company (revised September 22, 2022): https://ca.gsk.com/media/6205/paxil_pm_en.pdf
Paroxetine Sandoz 20 mg tablets consumer medicine information from NPS MedicineWise (revised November 2023): https://www.nps.org.au/assets/medicines/...
Morningside Healthcare Paroxetine 10 mg, 20 mg, 30 mg, 40 mg tablets package information leaflet for users on Medicines.org.uk (revised October 2023): https://www.medicines.org.uk/emc/files/pil.9582.pdf
Revised: June 2024
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