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Product Name: Nortriptyline
Generic Name: Nortriptyline
Common Brands: Aventyl, Pamelor, Primox
Pharmaceutical Categories: Antidepressants, Anti Anxiety
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Nortriptyline (trade names include Pamelor, Aventyl, Primox, Allegron, Noritren, Nortimer, Nortrilen, Sensaval) is a tricyclic antidepressant and anti-anxiety medication from non-selective monoamine reuptake inhibitors pharmacological group. This medicine is used to treat depressive disorders, anxiety, major depression, panic disorder, attention deficit hyperactivity disorder (ADHD), childhood nocturnal enuresis (bedwetting), primary nocturnal enuresis, irritable bowel syndrome, chronic fatigue syndrome, burning mouth syndrome (glossopyrosis), dysautonomia, migraine, cyclic vomiting syndrome, chronic pain, neurosis, neuralgia, neuropathic pain, diabetic peripheral neuropathy, postherpetic neuralgia, vulvodynia, tinnitus, temporomandibular joint disorder, reflex sympathetic dystrophy syndrome, labile affect in some neurological disorders, for smoking cessation. It is particularly effective in the treatment of endogenous depressions. Nortriptyline HCl works by affecting chemicals in the brain that may become unbalanced.
Customers also buy these medications from the same pharmacological classes:
Amineptine (Survector)
Amitriptyline (Elavil)
Amoxapine (Asendin)
Bupropion (Wellbutrin, Zyban)
Buspirone (Buspar)
Citalopram (Celexa)
Clomipramine (Anafranil)
Desipramine (Norpramin)
Desvenlafaxine (Pristiq)
Dosulepin (Prothiaden)
Doxepin (Sinequan)
Duloxetine (Cymbalta)
Escitalopram (Lexapro)
Fluvoxamine (Luvox)
Hydroxyzine (Atarax)
Imipramine (Tofranil)
Lofepramine (Gamanil)
Maprotiline (Ludiomil)
Melitracen (Adaptol)
Milnacipran (Savella)
Norethindrone (Aygestin)
Olanzapine (Zyprexa)
Opipramol (Insidon)
Paroxetine (Paxil)
Protriptyline (Vivactil)
Quetiapine (Seroquel)
Selegiline (Eldepryl)
Sertraline (Zoloft)
Trazodone (Desyrel)
Venlafaxine (Effexor)
Pharmaceutical and medical classifications:
ADHD medications
Analgesics
Anti depression medicines
Anti migraine meds
Anti-anxiety drugs
Moderate serotonin reuptake inhibitors
Pain relief pills
Secondary amine dibenzocycloheptene
Stop smoking products
Strong norepinephrine reuptake inhibitors
Tricyclic antidepressants
The Anatomical Therapeutic Chemical (ATC) classification system (developed by the World Health Organization):
N - Nervous system
N06 - Psychoanaleptics
N06A - Antidepressants
N06AA - Non-selective monoamine reuptake inhibitors
N06AA10 - Nortriptyline
Medical conditions for nortriptyline in the International Statistical Classification of Diseases and Related Health Problems:
Zoster [herpes zoster] - B02
Zoster with other nervous system involvement - B02.2
Postherpetic polyneuropathy - B02.23
Other postherpetic nervous system involvement - B02.29
Type 2 diabetes mellitus - E11
Type 2 diabetes mellitus with diabetic neuropathy - E11.4
Nicotine dependence - F17
Mood [affective] disorders - F30-F39
Major depressive disorder, single episode - F32
Major depressive disorder, recurrent - F33
Persistent mood (affective) disorders - F34
Anxiety, dissociative, stress-related, somatoform and other nonpsychotic mental disorders - F40-F48
Phobic anxiety disorders - F40
Other anxiety disorders - F41
Panic disorder [episodic paroxysmal anxiety] - F41.0
Reaction to severe stress, and adjustment disorders - F43
Reaction to severe stress, and adjustment disorders - F43
Other nonpsychotic mental disorders - F48
Nonpsychotic mental disorder, unspecified - F48.9
Attention-deficit hyperactivity disorders - F90
Other behavioral and emotional disorders with onset usually occurring in childhood and adolescence - F98
Enuresis not due to a substance or known physiological condition - F98.0
Migraine - G43
Other and unspecified polyneuropathies - G62
Pain, not elsewhere classified - G89
Chronic pain, not elsewhere classified - G89.2
Chronic pain syndrome - G89.4
Disorders of autonomic nervous system - G90
Familial dysautonomia [Riley-Day] - G90.1
Complex regional pain syndrome I (CRPS I) - G90.5
Other disorders of ear, not elsewhere classified - H93
Tinnitus - H93.1
Diseases of tongue - K14
Glossitis - K14.0
Glossodynia - K14.6
Irritable bowel syndrome - K58
Dentofacial anomalies [including malocclusion] - M26
Temporomandibular joint disorders - M26.6
Dorsalgia - M54
Other dorsalgia - M54.8
Occipital neuralgia - M54.81
Other and unspecified soft tissue disorders, not elsewhere classified - M79
Neuralgia and neuritis, unspecified - M79.2
Other disorders of urinary system - N39
Nocturnal enuresis - N39.44
Pain and other conditions associated with female genital organs and menstrual cycle - N94
Other specified conditions associated with female genital organs and menstrual cycle - N94.8
Vulvodynia - N94.81
Nausea and vomiting - R11
Cyclical vomiting syndrome unrelated to migraine - R11.15
Unspecified urinary incontinence - R32
Other and unspecified symptoms and signs involving the genitourinary system - R39
Functional urinary incontinence - R39.81
Other symptoms and signs involving the genitourinary system - R39.89
Pain, not elsewhere classified - R52
Malaise and fatigue - R53
Other malaise and fatigue - R53.8
Chronic fatigue, unspecified - R53.82
Pregnancy category:
C - Australia
C - United States (Risk cannot be ruled out)
Forms of active pharmaceutical ingredients (APIs):
Nortriptyline Base
Nortriptyline Ethyloarbamate
Nortriptyline Hydrochloride
Chemical, international, and other names of this drug:
5-(3-Methylaminopropylidene)-10,11-dihydro-5H-dibenzo(a,d)cycloheptene
5-(Alpha-Methylaminopropylidene)dibenzo(a,d)cyclohepta(1,4)diene
Amitryptyline, Demethyl-
Cloridrato de Nortriptilina
Demethylamitriptylene
Demethylamitriptyline
Demethylamitryptyline
Demethyl-Amitryptyline
Desitriptilina
Desmethylamitriptyline
Noramitriptyline
Nortriptilin
Nortriptilina
Nortriptilina Hidrocloruro
Nortriptuliin
Nortriptylene
Nortriptyliini
Nortriptylin
Nortriptylinhydrochlorid
Nortriptylini Hydrochloridum
Nortriptylinum
Nortryptiline
Nortryptyline
Most known trade names (brands and generics) worldwide:
Allegron - Eli Lilly, Aspen Pharmacare, King Pharmaceuticals
Apo-Nortriptyline - Apotex
Aventyl - Eli Lilly, AA Pharma, Aspen Pharmacare, Pharmascience, Ranbaxy
Martimil - Sanofi
Nordep - Orchid Chemicals & Pharmaceuticals
Norfenazin - Reig Jofre
Noritop - Tas Med India
Noritren - Lundbeck
Norpress - Mylan, Pacific Pharmaceuticals
Nortab - Bristol-Myers Squibb
Norterol - Tecnifar
Nortimer - Intas Pharmaceuticals
Nortin - Manas Pharma
Nortrilen - Lundbeck, B L Hua, DKSH, EU-Pharma, Euro Registratie, Four Star, Gerolymatos, Medcor Pharmaceuticals, NL Pharma
Nortrip - A. N. Pharmacia
Nortriptyline - Glenmark Pharmaceuticals, Mylan, Pro Doc, Ranbaxy, Sandoz, Teva, Zydus Lifesciences
Nortylin - Rekah
Ortrip - Pharmasant Laboratories, Central Poly Trading
Pamelor - Mallinckrodt, Novartis, Patheon, SpecGx, Tyco Healthcare
Paxtibi - Biomed, Spain
Primox - Sun Pharmaceutical Industries
Sensaval - Lundbeck
Sensival - Wallace Pharmaceuticals, Ilsung Pharmaceuticals, Lyfestyle, Pharmedic
Teva-Nortriptyline - Teva
Other medicines used in combinations with nortriptyline:
Chlordiazepoxide
Diazepam
Flupentixol
Fluphenazine
Gabapentin
Methylcobalamin
Perphenazine
Pregabalin
References and external sources:
Nortriptyline main article on Wikipedia: https://en.wikipedia.org/wiki/Nortriptyline
Nortriptyline compound on PubChem: https://pubchem.ncbi.nlm.nih.gov/compound/Nortriptyline
Nortriptyline Hydrochloride on PubChem: https://pubchem.ncbi.nlm.nih.gov/compound/Nortriptyline-Hydrochloride
Nortriptyline medicine on DrugBank: https://go.drugbank.com/drugs/DB00540
Nortriptyline FAQ on MedlinePlus (revised 08/15/2017): https://medlineplus.gov/druginfo/meds/a682620.html
Antidepressants (selective serotonin reuptake inhibitors, SSRIs, tricyclic antidepressants) FAQ on MedlinePlus: https://medlineplus.gov/antidepressants.html
Pamelor (Nortriptyline Hydrochloride) capsules drug label on DailyMed (revised December 4, 2024): https://dailymed.nlm.nih.gov/dailymed/drugInfo...
Zydus Nortriptyline Hydrochloride capsules drug label on DailyMed (revised December 11, 2024): https://dailymed.nlm.nih.gov/dailymed/drugInfo...
Pamelor (Nortriptyline HCl) capsules and oral solution official prescribing information and medication guide from the U.S. FDA (revised 10/2012): https://www.accessdata.fda.gov/drugsatfda_docs/label...
Pamelor (Nortriptyline HCl) 10 mg, 25 mg, 50 mg, 75 mg capsules prescribing information and medication guide from Mallinckrodt pharmaceutical company (revised 04/2019): https://www.mallinckrodt.com/Download.ashx...
Aventyl (Nortriptyline Hydrochloride) capsules USP 10 mg, 25 mg product monograph from AA Pharma Inc. (revised July 09, 2014): https://www.aapharma.ca/downloads/en/PIL/Aventyl_PM.pdf
Allegron (Nortriptyline Hydrochloride) tablets 10 mg, 25 mg consumer medicine information from NPS MedicineWise (revised May 2024): https://www.nps.org.au/assets/medicines/...
Glenmark Nortriptyline 10 mg, 25 mg, 50 mg film-coated tablets package information leaflet for patients on Medicines.org.uk (revised 02/2024): https://www.medicines.org.uk/emc/files/pil.9970.pdf
Revised: December 2024
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