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Product Name: Tolvaptan
Generic Name: Tolvaptan
Common Brands: Samsca
Pharmaceutical Categories: Aquaretic drugs
Where to buy Tolvaptan online:
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Tolvaptan (trade names include Samsca, Jinarc, Jynarque, Natrise, Resodim, Tolvat, Vaptan) is an aquaretic drug, diuretic medication from vasopressin antagonists pharmacological group. This medicine is used for the treatment of low blood sodium levels (hyponatremia) associated with congestive heart failure, cirrhosis, and the syndrome of inappropriate antidiuretic hormone (SIADH). It works as a selective, competitive vasopressin receptor 2 (V2) antagonist.
Related medications:
Amiloride, Furosemide (Frumil)
Atenolol (Tenormin)
Conivaptan (Vaprisol)
Enalapril (Vasotec)
Furosemide (Lasix)
Hydrochlorothiazide (Microzide)
Metoprolol (Lopressor, Toprol-XL)
Prazosin (Minipress)
Propranolol (Inderal)
Torsemide (Demadex)
Valsartan (Diovan)
Pharmaceutical and medical classifications:
Aquaretic drugs
diuretic medications
Vasopressin V2-receptor antagonists
Water pills
Water tablets
The Anatomical Therapeutic Chemical (ATC) classification system (developed by the World Health Organization):
C - Cardiovascular system
C03 - Diuretics
C03X - Other diuretics
C03XA - Vasopressin antagonists
C03XA01 - Tolvaptan
Medical conditions for tolvaptan in the International Statistical Classification of Diseases and Related Health Problems (ICD):
Hyperfunction of pituitary gland - E22
Syndrome of inappropriate secretion of antidiuretic hormone - E22.2
Other disorders of fluid, electrolyte and acid-base balance - E87
Hypo-osmolality and hyponatremia - E87.1
Heart failure - I50
Fibrosis and cirrhosis of liver - K74
Pregnancy category:
D - Australia
C - United States (Risk cannot be ruled out)
Forms of active pharmaceutical ingredients (APIs):
Tolvaptan Base
Chemical, international, and other names of this drug:
Tolvaptana
Tolvaptano
Tolvaptanum
Most known trade names (brands and generics) worldwide:
Jinarc - Otsuka Pharmaceutical, AndersonBrecon
Jynarque - Otsuka Pharmaceutical
Natrise - Sun Pharmaceutical Industries
Resodim - Lupin
Samsca - Otsuka Pharmaceutical
Tenax - Edallia Pharmaceuticals
Tolaqua - Abhay Pharma
Tolsama - MSN Laboratories, Mutual Medical Agencies
Tolvaptoris - Steris Healthcare
Tolvasca - Glenmark Pharmaceuticals, Mili Health Care
Tolvat - MSN Laboratories, Shaurya Internationa
Tvaptan - Lahar Pharmaceuticals
Vaptan - Steadfast MediShield
References and external sources:
Tolvaptan main article on Wikipedia: https://en.wikipedia.org/wiki/Tolvaptan
Tolvaptan compound on PubChem: https://pubchem.ncbi.nlm.nih.gov/compound/Tolvaptan
Tolvaptan medicine on DrugBank: https://www.drugbank.ca/drugs/DB06212
Tolvaptan for low blood sodium FAQ on MedlinePlus (revised 08/15/2018): https://medlineplus.gov/druginfo/meds/a609033.html
Tolvaptan for kidney disease FAQ on MedlinePlus (revised 06/15/2020): https://medlineplus.gov/druginfo/meds/a620041.html
Samsca (Tolvaptan) tablets drug label on DailyMed (revised November 9, 2022): https://dailymed.nlm.nih.gov/dailymed/drugInfo...
Jynarque (Tolvaptan) tablets and kit drug label on DailyMed (revised November 8, 2022): https://dailymed.nlm.nih.gov/dailymed/drugInfo...
Samsca (Tolvaptan) tablets for oral use 15 mg and 30 mg official prescribing information and medication guide from the U.S. FDA (revised 04/2021): https://www.accessdata.fda.gov/drugsatfda_docs/label...
Samsca (Tolvaptan) tablets for oral use 15 mg and 30 mg prescribing information and medication guide from Otsuka Pharmaceutical company (revised 04/2021): https://www.otsuka-us.com/media/static/Samsca-PI.pdf
Jynarque (Tolvaptan) tablets for oral use 15 mg, 30 mg, 45 mg, 60 mg and 90 mg prescribing information and medication guide from Otsuka Pharmaceutical (revised 10/2020): https://www.otsuka-us.com/media/static/JYNARQUE-PI.pdf
Samsca (Tolvaptan) tablets official website powered by Otsuka America Pharmaceutical, Inc.: https://www.samsca.com/
Samsca (Tolvaptan) 7.5 mg, 15 mg, 30 mg tablets package information leaflet for users on Medicines.org.uk (revised 08/2022): https://www.medicines.org.uk/emc/files/pil.6635.pdf
Jinarc (Tolvaptan) 15 mg, 30 mg, 45 mg, 60 mg, 90 mg tablets package information leaflet for users on Medicines.org.uk (revised 11/2022): https://www.medicines.org.uk/emc/files/pil.6846.pdf
Revised: February 2024
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