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Product Name: Melatonin
Generic Name: Melatonin
Common Brands: Circadin, Meloset, Slenyto
Pharmaceutical Categories: Sleep Aid
Where to buy Melatonin online:
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Melatonin (trade names include Bio-Melatonin, Circadin, Extra Strength Melatonin, GNC Melatonin, Liquid Melatonin, Melatol, Melatonin Life Extension, Melatonin Natrol, Melatonin Nature's Bounty, Melatonin Now Foods, Melatonin Puritan's Pride, Melatonin Schiff, Melatonin Source Naturals, Melatonin Fast Dissolve, Melatonin Gummies, Melatonina Lek-Am, Melatonina Millenium, Melatonina Sundown, Melaxen, Meloset, Melovine, Nature Made Melatonin, Sleepzz Melatonine, Slenyto, Spring Valley Melatonin, Sublingual Melatonin, VitaMelts Sleep) is a natural hormone, sedative and hypnotic medicine from melatonin receptor agonists pharmacological group. It produced by the pineal gland and regulates entrainment (synchronization) of the circadian rhythms including sleep and wakefulness, blood pressure regulation, seasonal reproduction, and many other properties.
As a medication melatonin is used for the treatment of insomnia, delayed sleep phase syndrome, insomnia associated with attention deficit-hyperactivity disorder (ADHD), insomnia caused by beta-blocker drugs, other sleep disorders; for blood pressure control in people with nocturnal hypertension and essential hypertension; patients with circadian rhythm sleep disorders; sleep problems of people who work rotating or night shifts; sleep problems in people with moderate to severe dementia due to Alzheimer's disease; to help with sundowning in people with dementia; to improve sleep in minimal cognitive impairment; sleep problems in children with developmental disorders including autism, cerebral palsy, intellectual disabilities; to reduce the effects of jet lag, shift work; rapid eye movement sleep behavior disorder; to reduce the side effects of stop smoking; some types of headaches such as migraine and cluster headaches; for recovery after surgery; agitation caused by anesthesia; for birth control; for total cholesterol reduction.
Other indications include tinnitus, ringing in the ears, endometriosis, bipolar disorder, chronic obstructive pulmonary disease (COPD), seasonal affective disorder, gallstones, dysmenorrhea, heartburn, abdominal pain, delirium, stress, metabolic syndrome, aging, menopause, epilepsy, infertility, exercise performance, Helicobacter pylori, acid reflux disease, involuntary movement disorder, tardive dyskinesia, postural tachycardia syndrome, osteoporosis, irritable bowel syndrome, inability to control urination, benign prostatic hyperplasia, ulcerative colitis, age-related vision loss, schizophrenia, sarcoidosis, restless leg syndrome, fibromyalgia, jaw pain, chronic fatigue syndrome, nonalcoholic liver disease, as an antioxidant, for protection from radiation and oxidative stress, in oncology, psychiatry, veterinary.
Because of high efficiency and safety sleep pills and dietary supplements containing melatonin are very popular in most of countries worldwide, including USA, Canada, UK, EU, Australia.
Customers also buy these medications from the same pharmacological classes:
Alprazolam (Xanax)
Amitriptyline (Elavil)
Armodafinil (Nuvigil)
Bromazepam (Lexotan)
Butobarbital (Soneryl)
Chlorpromazine (Thorazine)
Clonazepam (Klonopin, Rivotril)
Dexmedetomidine (Precedex)
Diazepam (Valium)
Doxepin (Sinequan)
Eszopiclone (Lunesta)
Flunitrazepam (Rohypnol)
Hydroxyzine (Atarax)
Lorazepam (Ativan)
Midazolam (Dormicum)
Mirtazapine (Remeron)
Modafinil (Provigil)
Niaprazine (Nopron)
Nitrazepam (Mogadon)
Pentobarbital (Nembutal)
Pyrithyldione (Presidon)
Quetiapine (Seroquel)
Ramelteon (Rozerem)
Tasimelteon (Hetlioz)
Temazepam (Restoril)
Tizanidine (Zanaflex)
Trazodone (Desyrel)
Zaleplon (Sonata)
Zolpidem (Ambien)
Zopiclone (Imovane)
Pharmaceutical and medical classifications:
Antioxidants
Anxiolytics
Cancer drugs
Dietary supplements
Hypnotics
Indoleamines
Natural compounds
Natural hormones
Naturally occurring hormones
Nutraceutical products
Nutritions
OTC medications
Pain relief medicines
Sedatives
Sleep aid pills
Veterinary, pet meds
The Anatomical Therapeutic Chemical (ATC) classification system (developed by the World Health Organization):
N - Nervous system
N05 - Psycholeptics
N05C - Hypnotics and sedatives
N05CH - Melatonin receptor agonists
N05CH01 - Melatonin
Medical conditions for melatonin in the International Statistical Classification of Diseases and Related Health Problems:
Other bacterial agents as the cause of diseases classified elsewhere - B96
Other specified bacterial agents as the cause of diseases classified elsewhere - B96.8
Helicobacter pylori [H. pylori] as the cause of diseases classified elsewhere - B96.81
Neoplasms - C00-D49
Sarcoidosis - D86
Other nutritional deficiencies - E63
Nutritional deficiency, unspecified - E63.9
Disorders of lipoprotein metabolism and other lipidemias - E78
Pure hypercholesterolemia - E78.0
Other and unspecified metabolic disorders - E88
Other specified metabolic disorders - E88.8
Metabolic syndrome and other insulin resistance - E88.81
Metabolic syndrome - E88.810
Exposure to radiation - E926
Dementia in other diseases classified elsewhere - F02
Delirium due to known physiological condition - F05
Nicotine dependence - F17
Schizophrenia - F20
Bipolar disorder - F31
Major depressive disorder, recurrent - F33
Sleep disorders not due to a substance or known physiological condition - F51
Intellectual disabilities - F70-F79
Pervasive developmental disorders - F84
Autistic disorder - F84.0
Attention-deficit hyperactivity disorders - F90
Dystonia - G24
Drug induced dystonia - G24.0
Drug induced subacute dyskinesia - G24.01
Other extrapyramidal and movement disorders - G25
Restless legs syndrome - G25.81
Alzheimer's disease - G30
Other degenerative diseases of nervous system, not elsewhere classified - G31
Other specified degenerative diseases of nervous system - G31.8
Epilepsy and recurrent seizures - G40
Other headache syndromes - G44
Cluster headaches and other trigeminal autonomic cephalgias (TAC) - G44.0
Sleep disorders - G47
Insomnia - G47.0
Circadian rhythm sleep disorders - G47.2
Circadian rhythm sleep disorder, delayed sleep phase type - G47.21
Circadian rhythm sleep disorder, jet lag type - G47.25
Parasomnia - G47.5
REM sleep behavior disorder - G47.52
Cerebral palsy - G80
Disorders of autonomic nervous system - G90
Postural orthostatic tachycardia syndrome [POTS] - G90.A
Other retinal disorders - H35
Degeneration of macula and posterior pole - H35.3
Unspecified macular degeneration - H35.30
Other disorders of ear, not elsewhere classified - H93
Tinnitus - H93.1
Essential (primary) hypertension - I10
Secondary hypertension - I15
Other secondary hypertension - I15.8
Other chronic obstructive pulmonary disease - J44
Gastro-esophageal reflux disease - K21
Gastro-esophageal reflux disease without esophagitis - K21.9
Ulcerative colitis - K51
Irritable bowel syndrome - K58
Other diseases of liver - K76
Fatty (change of) liver, not elsewhere classified - K76.0
Cholelithiasis - K80
Other and unspecified soft tissue disorders, not elsewhere classified - M79
Fibromyalgia - M79.7
Osteoporosis without current pathological fracture - M81
Benign prostatic hyperplasia - N40
Endometriosis - N80
Pain and other conditions associated with female genital organs and menstrual cycle - N94
Menopausal and other perimenopausal disorders - N95
Menopausal and female climacteric states - N95.1
Female infertility - N97
Abdominal and pelvic pain - R10
Other abdominal pain - R10.8
Generalized abdominal pain - R10.84
Heartburn - R12
Unspecified urinary incontinence - R32
Malaise and fatigue - R53
Other malaise and fatigue - R53.8
Chronic fatigue, unspecified - R53.82
Age-related physical debility - R54
Other general symptoms and signs - R68
Other general symptoms and signs - R68.8
Jaw pain - R68.84
Other complications of surgical and medical care, not elsewhere classified - T88
Other complications of anesthesia - T88.5
Other complications of anesthesia - T88.59
Activity codes - Y93
Activities involving other muscle strengthening exercises - Y93.B
Activity, other involving muscle strengthening exercises - Y93.B9
Encounter for contraceptive management - Z30
Encounter for other postprocedural aftercare - Z48
Encounter for other specified postprocedural aftercare - Z48.8
Encounter for surgical aftercare following surgery on specified body systems - Z48.81
Problems related to life management difficulty - Z73
Stress, not elsewhere classified - Z73.3
Pregnancy category:
B1 - Australia
A - United States (No risk in controlled human studies)
Forms of active pharmaceutical ingredients (APIs):
Melatonin Base
Chemical, international, and other names of this drug:
5-Methoxy-N-acetyltryptamine
Acetamide, N-(2-(5-methoxy-1H-indol-3-yl)ethyl)-
Acetamide, N-(2-(5-methoxyindol-3-yl)ethyl)-
Meileatoinin
Melatoniin
Melatoniini
Melatonina
Melatoninas
Melatonine
Melatonino
Melatonins
Melatoninum
N-(2-(5-Methoxy-1H-indol-3-yl)ethyl)acetamide
N-(2-(5-Methoxyindol-3-yl)ethyl)acetamide
N-Acetyl-5-Methoxytryptamine
N-Acetyl-5-Methoxy Tryptamine
Most known trade names (brands and generics) worldwide:
Bio-Melatonin - Pharma Nord
Circadin - RAD Neurim Pharmaceuticals, Aspen Pharmacare
Cronocaps - Productos Medix
Extra Strength Melatonin - Now Foods, Sundown Naturals
Filfresh - Grievers Remedies
GNC Melatonin - Total Nutrition Corporation
Lamrest - Tas Med India
Liquid Melatonin - Life Extension, Solgar
Maximum Strength Melatonin - 21st Century HealthCare
Melatol - Elisium
Melatonin - 21st Century HealthCare, Country Life Vitamins, Life Extension, Natrol, Nature's Bounty, Now Foods, Puritan's Pride, Schiff, Solgar, Source Naturals
Melatonin Fast Dissolve - Natrol, Puritan's Pride
Melatonin Gummies - Sundown Naturals
Melatonin Gummy - Puritan's Pride
Melatonina - Arama Laboratorios, GNC-FASA, Laropharm, Lek-Am Przedsiebiorstwo Farmaceutyczne, Millenium Natural Health Products, Sundown Naturals
Melatonin TR - Natrol
Melaxen - Unipharm
Meloset - Aristo Pharmaceuticals
Melotin - Arrotex Pharmaceuticals
Melovine - Ceva Animal Health, Ceva Sante Animale
Nature Made Melatonin - Pharmavite
Normolem - Teva
Royaline - Pharmalat Laboratorios
Sleep with Melatonin - Zarbee's Naturals
Sleepwell - Trianon International
Sleepzz Melatonine Time Release - Vemedia
Slenyto - Aspen Pharma, Neurim Pharmaceuticals
Spring Valley Melatonin - Walmart
Sublingual Melatonin Cherry - Puritan's Pride
VitaMelts Sleep - Pharmavite
Other medicines used in combinations with melatonin:
Alprazolam
Calcium
Chamomile
Folic Acid
Gamma-Aminobutyric Acid
Glycine
Inositol
L-Theanine
Magnesium
Oxitriptan
Taurine
Ubidecarenone
Valerian
Vitamins
Zinc
Zolpidem
References and external sources:
Melatonin main article on Wikipedia: https://en.wikipedia.org/wiki/Melatonin
Melatonin as a medication and supplement article on Wikipedia: https://en.wikipedia.org/wiki/Melatonin_as_a_medication_and_supplement
Melatonin compound on PubChem: https://pubchem.ncbi.nlm.nih.gov/compound/Melatonin
Melatonin medicine on DrugBank: https://go.drugbank.com/drugs/DB01065
Melatonin FAQ on MedlinePlus (revised 07/09/2024): https://medlineplus.gov/druginfo/natural/940.html
Safrel Melatonin tablets 3 mg drug label on DailyMed (revised August 30, 2020): https://dailymed.nlm.nih.gov/dailymed/drugInfo...
Deseret Biologicals Melatonin liquid drug label on DailyMed (revised April 1, 2024): https://dailymed.nlm.nih.gov/dailymed/drugInfo...
Slenyto (Melatonin) 1 mg and 5 mg prolonged release tablets product information from The Therapeutic Goods Administration (revised 22 May 2020): https://www.tga.gov.au/sites/default/files/...
Circadin (Melatonin) 2 mg tablets consumer medicine information from NPS MedicineWise (revised January 2021): https://www.nps.org.au/assets/medicines/...
Melotin (Melatonin) 2 mg tablets consumer medicine information from MedSafe (revised November 2021): https://www.medsafe.govt.nz/consumers/cmi/m/melotin.pdf
Rafarm Melatonin 3 mg film-coated tablets package information leaflet for users on Medicines.org.uk (revised August 2021): https://www.medicines.org.uk/emc/files/pil.10405.pdf
Revised: January 2025
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