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Product Name: Sulfamethoxazole, Trimethoprim
Generic Name: Sulfamethoxazole, Trimethoprim
Common Brands: Bactrim, Septra
Pharmaceutical Categories: Antibiotics, Anti-Infectives, Antiparasitic
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Sulfamethoxazole with Trimethoprim (trade names include Bactrim, Septra, Co-Trimoxazole, Bactrim-DS, Septra-DS, Apo-Sulfatrim, Biseptol, Bactrim-F, Biseptrim, Cotrim, Cotrimoxazol, Eusaprim Forte, Novo-Trimel DS, Sepmax, Septrin, SMZ-TMP, Sulfatrim, Trimeth / Sulfa, Cotrimoxazole, Bactrim Forte) is a combined antibacterial medication from "sulfonamides and trimethoprim" pharmacological group. This medicine is used to treat various bacterial infections such as respiratory tract, renal and urinary tract, gastrointestinal tract, skin and wound, eye and ear infections, inclusion conjunctivitis, otitis media, septicaemias, travelers' diarrhea, cholera, pneumocystis pneumonia in people with HIV/AIDS, malaria, toxoplasmosis, trachoma, in veterinary, and other infections caused by sensitive organisms. It works by killing sensitive bacteria.
Customers also buy these medications from the same pharmacological classes:
Amoxicillin (Amoxil)
Amoxicillin, Clavulanate Potassium (Augmentin)
Azithromycin (Zithromax)
Cefaclor (Ceclor)
Cefadroxil (Duricef)
Chloramphenicol (Chloromycetin)
Ciprofloxacin (Cipro)
Clarithromycin (Biaxin)
Clindamycin (Cleocin)
Cycloserine (Seromycin)
Doxycycline (Vibramycin)
Erythromycin (Ilosone)
Ethionamide (Trecator-SC)
Levofloxacin (Levaquin)
Linezolid (Zyvox)
Metronidazole (Flagyl)
Minocycline (Minocin)
Moxifloxacin (Avelox)
Nalidixic Acid (Neggram)
Nitrofurantoin (Furadantin)
Norfloxacin (Noroxin)
Ofloxacin (Floxin, Ocuflox)
Roxithromycin (Rulide)
Sulfadiazine, Tetroxoprim (Tibirox)
Sulfadiazine, Trimethoprim (Triglobe)
Sulfamerazine, Trimethoprim (Berlocombin)
Sulfamethazine, Trimethoprim (Trimerazin)
Sulfametrole, Trimethoprim (Lidaprim)
Sulfamoxole, Trimethoprim (Supristol)
Tetracycline (Sumycin)
Pharmaceutical and medical classifications:
Anti infective drugs
Antibacterial combinations
Antibiotics
Combined sulfonamides
Topical sulfonamides used in the treatment of dermatological diseases
Veterinary, pet meds
The Anatomical Therapeutic Chemical (ATC) classification system (developed by the World Health Organization):
J - Antiinfectives for systemic use
J01 - Antibacterials for systemic use
J01E - Sulfonamides and trimethoprim
J01EE - Combinations of sulfonamides and trimethoprim, incl. derivatives
J01EE01 - Sulfamethoxazole and trimethoprim
Medical conditions for sulfamethoxazole with trimethoprim in the International Statistical Classification of Diseases and Related Health Problems:
Ill-defined intestinal infections - 009
Infectious diarrhea - 009.2
Cholera - A00
Typhoid and paratyphoid fevers - A01
Other salmonella infections - A02
Shigellosis - A03
Other bacterial intestinal infections - A04
Diarrhoea and gastroenteritis of presumed infectious origin - A09
Brucellosis - A23
Scarlet fever - A38
Meningococcal infection - A39
Streptococcal septicaemia - A40
Other septicaemia - A41
Erysipelas - A46
Gonococcal infection - A54
Trachoma - A71
Other diseases caused by chlamydiae - A74
Chlamydial conjunctivitis - A74.0
Plasmodium falciparum malaria - B50
Plasmodium vivax malaria - B51
Plasmodium malariae malaria - B52
Other specified malaria - B53
Unspecified malaria - B54
Toxoplasmosis - B58
Pneumocystosis - B59+
Bacterial meningitis, not elsewhere classified - G00
Intracranial and intraspinal abscess and granuloma - G06
Suppurative and unspecified otitis media - H66
Acute pharyngitis - J02
Acute laryngitis and tracheitis - J04
Pneumonia due to Haemophilus influenzae - J14
Bacterial pneumonia, not elsewhere classified - J15
Acute bronchitis - J20
Acute bronchiolitis - J21
Chronic sinusitis - J32
Chronic diseases of tonsils and adenoids - J35
Chronic laryngitis and laryngotracheitis - J37
Unspecified chronic bronchitis - J42
Bronchiectasis - J47
Cholecystitis - K81
Other diseases of biliary tract - K83
Impetigo - L01
Cutaneous abscess, furuncle and carbuncle - L02
Cellulitis - L03
Other local infections of skin and subcutaneous tissue - L08
Acne - L70
Other follicular disorders - L73
Osteomyelitis - M86
Acute tubulo-interstitial nephritis - N10
Chronic tubulo-interstitial nephritis - N11
Cystitis - N30
Urethritis and urethral syndrome - N34
Inflammatory diseases of prostate - N41
Salpingitis and oophoritis - N70
Other symptoms and signs involving the digestive system and abdomen - R19
Certain early complications of trauma - T79
Pregnancy category:
C - Australia
C - United States (Risk cannot be ruled out)
Forms of active pharmaceutical ingredients (APIs):
Sulfamethoxazole Base
Sulfamethoxazole Lysine
Sulfamethoxazole Sodium
Trimethoprim Base
Trimethoprim Hydrochloride
Trimethoprim Sulfate
Chemical, international, and other names of this drug:
Cotrimossazolo
Cotrimoxazol
Co-Trimoxazol
Cotrimoxazole
Co-Trimoxazole
Cotrimoxazolum
Co-Trimoxizole
Co-Trimoxizolum
Ko-Trimoksasool
Kotrimoksazol
Ko-Trimoksazol
Ko-Trimoksazols
Kotrimoxazol
Ko-Trimoxazol
SXT
TMPS
TMP-SMX
TMP-SMZ
TMP-Sulfa
Trimetoprim / Sulfametoksasool
Trimetoprim / Sulfametoksazol
Trimetoprim-Sulfametoksazol
Trimetoprim-Sulfametoxazol
Most known trade names (brands and generics) worldwide:
Abactrim - Roche
Anitrim - Italmex
Antrima - Abbott
Apo-Sulfatrim - Apotex, Hind Wing, Nhan Tam, Pharmaforte
Apo-Sulfatrim DS - Apotex
Bacfar-F - Elofar Laboratorio Farmaceutico
Bacidal - Medichem Pharmaceuticals, United Laboratories
Bactelan - Quimica y Farmacia
Bactrim - Roche, Abbott, AR Scientific, Cenexi, Deva Holding, DKSH, Galenika, Investi Farma, Mutual Pharmaceuticals, Nicholas Piramal, Sun Pharmaceutical Industries, Teriak Laboratoires Pharmaceutique
Bactrim-DS - Roche, Abbott, AR Scientific, Mutual Pharmaceuticals, Piramal Healthcare, Sun Pharmaceutical Industries
Bactrim-F - Roche
Bactrim Forte - Roche, Zuellig Pharma
Bactrim Pediatric - Roche, AR Scientific
Bactrimel - Roche
Bactropin - Cimed Industria de Medicamentos, Son's Laboratorios Quimica
Benectrin - EMS Industria Farmaceutica
Berlocid - Berlin-Chemie
Bioprim - Bioresearch de Mexico, Norma Greece
Biseptol - Polfa Pabianice, Medana Pharma, Polfa Warszawa
Biseptrim - GlaxoSmithKline
Ciplin-DS - Cipla
Cotrim - AbZ-Pharma, CT-Arzneimittel, Medochemie, Ratiopharm, Sandoz, Spirig Pharma
Cotrim D.S. - Teva, Komedic, Medochemie
Cotrim Forte - CT-Arzneimittel, Ratiopharm, Spirig Pharma
Cotrim-E - Ratiopharm
Cotrim-K - Ratiopharm
Cotrimhexal Forte - Hexal
Cotrimoxazol - Aliud Pharma, Mipharmco, Sanitas Laboratorio Chimico Farmaceutico
Cotrimoxazol Forte - Aliud Pharma, Chile Laboratorios, Sanitas Laboratorio Chimico Farmaceutico
Co-Trimoxazol - Akrikhin, Sandoz, Teva
Co-Trimoxazol Forte - Helvepharm, Teva
Cotrimoxazole - Claris Lifesciences, Ratiopharm, Vatchem-Pharmacy
Cotrimoxazole Forte - BOIE
Co-Trimoxazole - Mayne Pharma, Pascual Laboratories, Sanavita Pharmaceuticals
Cotrimoxazole DS - AstraZeneca
CotrimStada - Stada, Khuong Duy Pharmaceutical
CotrimStada Forte - Stada
DHAtrin - Drug Houses of Australia, U.S. Summit
Dientrin - Sanofi
Diseptyl Forte - Rekah
Ectaprim - Liomont Laboratorios
Embatrim - Flamingo Pharmaceuticals, Pasteur Pharmaceuticals
Embatrim Forte - Flamingo Pharmaceuticals
Eusaprim - GlaxoSmithKline
Eusaprim Forte - GlaxoSmithKline
Globaxol - GX International, Metro Drug Distribution
Infectrin - Boehringer Ingelheim
Lagatrim - Lagap, Alliance Pharmaceuticals
Licoprima - Berlico Mulia Farma
Maxtrim - Bristol-Myers Squibb, SSP Laboratories
Mediprim - Medika, Switzerland
Momentol - Bristol-Myers Squibb
Nopil - Mepha, Medimport
Nopil Forte - Mepha
Novo-Trimel - Novopharm
Novo-Trimel DS - Novopharm
Nu-Cotrimox - Nu-Pharm
Oriprim - Cadila Pharmaceuticals, Zydus Cadila
Polibatrin - Teva, IVAX
Primadex - Dexa Medica Pharm & Chem
Primadex Forte - Dexa Medica Pharm & Chem
Primotren - Lek
Purbac - Aspen Pharmacare
Resprim - Alphapharm, Merck, Serono, Summit, Teva, Zuellig Pharma
Resprim Forte - Alphapharm, Teva
Sanprima - Sanbe Farma
Sepmax - GlaxoSmithKline
Septra - GlaxoSmithKline, Asiatic Laboratories, Aspen Pharmacare, Aspri Pharma Canada, King Pharmaceuticals, Monarch Pharmaceuticals, Pfizer, Triton Pharma
Septra-DS - GlaxoSmithKline, Monarch Pharmaceuticals, Pfizer
Septra Pediatric - GlaxoSmithKline, Pfizer
Septran - GlaxoSmithKline
Septrin - GlaxoSmithKline, Alcala Farma Laboratorios, Arrow Pharma, Aspen, Celltech, Draxis Health, Gerolymatos, Jubilant HollisterStier, P & D Pharmaceuticals, PharmaSwiss, PharmaTech, Samil Pharmaceutical, Sigma Pharmaceuticals, UCB Pharma
Septrin Forte - GlaxoSmithKline, Sigma Pharmaceuticals, Zuellig Pharma
Septrin Paediatric - GlaxoSmithKline, Zuellig Pharma
Septrin-DS - GlaxoSmithKline
Septrin-F - GlaxoSmithKline, Sigma Pharmaceuticals
Servitrim - Novartis, Sandoz, Servipharm, Zuellig Pharma
SMZ-TMP - Bristol-Myers Squibb
Soltrim - Almirall, Importadora y Manufacturera Bruluart
Sulfamethoprim - Par Pharmaceutical, Quad Pharmaceuticals
Sulfamethoxazole, Trimethoprim - Mayne Pharma, Pliva, Sandoz, Sicor Pharmaceuticals, Teva
Sulfamethoxazole, Trimethoprim Double Strength - Eon Labs, Mutual Pharmaceuticals, Roxane Laboratories, Teva
Sulfatrim - Alpharma, Mekophar Chemical-Pharmaceutical, Superpharm
Sulfatrim-DS - Superpharm
Sumetrolim - Egis, Medimpex Trading
TMS - TAD Pharma, Dr. Grossmann Pharmaca
Trimeth / Sulfa - Alpharma, Naska
Trimetoprim Sulfa - S.M. Laboratorio Farmaceutico, Fournier, GEA
Trimexazol - Sanofi, ICN Pharmaceuticals, Valeant Pharmaceuticals
Trimezol - Biofarma Farmaceutica
Trimoxazole - Sandoz
Trisulfa - Jaapharm Canada
Other medicines used in combinations with sulfamethoxazole and trimethoprim:
Attapulgite
Bromhexine
Carbocisteine
Cineole
Citiolone
Dihydrocodeine
Erythromycin
Guaiacol
Guaifenesin
Niaouli Oil
Peru Balsam
Phenylephrine
Sulfogaiacol
Thenoic Acid
References and external sources:
Trimethoprim/sulfamethoxazole main article on Wikipedia: https://en.wikipedia.org/wiki/Trimethoprim/sulfamethoxazole
Sulfamethoxazole and trimethoprim compound on PubChem: https://pubchem.ncbi.nlm.nih.gov/compound/Sulfamethoxazole-and-trimethoprim
Sulfamethoxazole medicine on DrugBank: https://go.drugbank.com/drugs/DB01015
Trimethoprim medication on DrugBank: https://go.drugbank.com/drugs/DB00440
Co-trimoxazole FAQ on MedlinePlus (revised 01/15/2022): https://medlineplus.gov/druginfo/meds/a684026.html
Bactrim (Sulfamethoxazole and Trimethoprim) and Bactrim DS tablets drug label on DailyMed (revised April 29, 2021): https://dailymed.nlm.nih.gov/dailymed/drugInfo...
Proficient Rx Sulfamethoxazole and Trimethoprim tablets drug label on DailyMed (revised October 1, 2022): https://dailymed.nlm.nih.gov/dailymed/lookup...
Bactrim (Sulfamethoxazole and Trimethoprim) tablets official prescribing information from the U.S. FDA (revised April 2021): https://www.accessdata.fda.gov/drugsatfda_docs/label...
Bactrim (Sulfamethoxazole and Trimethoprim) injection for intravenous use official prescribing and patient counseling information from the U.S. FDA (revised 03/2017): https://www.accessdata.fda.gov/drugsatfda_docs/label...
Bactrim DS tablets and Bactrim oral suspension (Sulfamethoxazole and Trimethoprim) consumer medicine information from NPS MedicineWise (revised July 2019): https://www.nps.org.au/assets/medicines/...
Septra (Sulfamethoxazole and Trimethoprim) and Septra DS tablets prescribing information from Pfizer pharmaceutical company (revised 12/2020): http://labeling.pfizer.com/ShowLabeling.aspx?id=706
Septrin (Sulfamethoxazole and Trimethoprim) 400/80 mg and 800/160 mg oral tablets product information from Therapeutic Goods Administration (revised 14 May 2018): https://www.ebs.tga.gov.au/ebs/picmi/...
Aspen Co-Trimoxazole Forte 160mg/800mg tablets package information leaflet from Medicines.org.uk (revised September 2022): https://www.medicines.org.uk/emc/files/pil.6997.pdf
Revised: February 2024
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