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Product/Generic Name: Hydrochlorothiazide, Irbesartan
Common Brands: Avalide
Pharmaceutical Categories: Cardio, Blood Pressure, Cholesterol
Where to buy Hydrochlorothiazide, Irbesartan online:
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Irbesartan with Hydrochlorothiazide (trade names include Avalide, Aprozide, Avapro HCT, Co-Aprovel, Co-Irabel, CoAprovel, Irbesartan HCTZ, Irovel H, Karvezide, Sandoz Irbesartan HCT) is a combined medication containing antihypertensive drug Irbesartan (from angiotensin II antagonists) and diuretic Hydrochlorothiazide (from thiazides pharmacological group). This medicine is used for the treatment of high blood pressure (hypertension). It helps to prevent strokes, heart attacks, kidney problems. Irbesartan works by relaxing the blood vessels. Hydrochlorothiazide helps the kidneys to remove fluid from the body.
Related medications:
Amlodipine (Norvasc)
Atenolol (Tenormin)
Azilsartan (Edarbi)
Bisoprolol (Zebeta)
Candesartan (Atacand)
Diltiazem (Cardizem)
Enalapril (Vasotec)
Eprosartan (Teveten)
Hydrochlorothiazide, Losartan (Hyzaar)
Hydrochlorothiazide, Olmesartan (Benicar HCT)
Hydrochlorothiazide, Telmisartan (Micardis HCT)
Hydrochlorothiazide, Valsartan (Diovan HCT)
Indapamide (Lozol)
Irbesartan (Avapro)
Labetalol (Trandate)
Losartan (Cozaar)
Metoprolol (Lopressor, Toprol-XL)
Nifedipine (Adalat)
Olmesartan (Benicar)
Propranolol (Inderal)
Tasosartan (Verdia)
Telmisartan (Micardis)
Terazosin (Hytrin)
Valsartan (Diovan)
Verapamil (Calan)
Pharmaceutical and medical classifications:
Angiotensin II receptor antagonists
Antihypertensive drugs
Cardiovascular medications
Combined antihypertensive medicines
Thiazide diuretics with angiotensin II receptor antagonists
The Anatomical Therapeutic Chemical (ATC) classification system (developed by the World Health Organization):
C - Cardiovascular system
C09 - Agents acting on the renin-angiotensin system
C09D - Angiotensin II receptor blockers (ARBS), combinations
C09DA - Angiotensin II receptor blockers (ARBs) and diuretics
C09DA04 - Irbesartan and diuretics
Medical conditions for irbesartan with hydrochlorothiazide in the International Statistical Classification of Diseases and Related Health Problems (ICD):
Essential (primary) hypertension - I10
Acute myocardial infarction - I21
Complications and ill-defined descriptions of heart disease - I51
Pregnancy category:
D - Australia
D - United States (Positive evidence of risk)
Forms of active pharmaceutical ingredients (APIs):
Irbesartan Base
Irbesartan Hydrochloride Sesquihydrate
Hydrochlorothiazide Base
Hydrochlorothiazide Hydrochloride
Chemical, international, and other names of this drug:
Irbesartane
Irbesartanum
Irbezartan
Irbisartan
Chlorsulfonamidodihydrobenzothiadiazine Dioxide
Clorhidrato Hidroclorotiazida
Dihydrochlorothiazid
Dihydrochlorothiazide
HCTZ
HCZ
Hidrochlortiazid
Hidroclorotiazida
Hidrohlorotiazid
Hydrochloorthiazide
Hydrochlorothiazid
Hydrochlorothiazidum
Hydrochlorthiazide
Hydrochlorthiazidum
Hydroklooritiatsidi
Hydroklortiazid
Idroclorotiazide
Most known trade names (brands and generics) worldwide:
Abisart HCT - Alphapharm
Apo-Irbesartan HCTZ - Apotex
Aprovel HCT - Sanofi
Aprozide - Sanofi, The Harvard Drug Group
Arbesta Plus - Ali Raif Pharmaceutical Industry
Avalide - Sanofi, Bristol-Myers Squibb
Avapro HCT - Bristol-Myers Squibb
Bart H - Momenta Farmaceutica
Co-Aprovel - Sanofi
Co-Irabel - KRKA
Co-Irbewin - Sanofi
Co-Irda - Nobel Ilac
Co-Irvell - Novell Pharmaceutical
CoAprovel - Sanofi, Bristol-Myers Squibb, DKSH, IDS Group, Metro Drug Distribution, The Glory Medicina, Zuellig Pharma
Converide - Medochemie
Ifirmacombi - KRKA
Irbenida Plus - Hemofarm
Irbesartan Comp. - AbZ-Pharma, Hexal, Ratiopharm
Irbesartan HCT - Actavis, Sandoz
Irbesartan HCTZ - Pro Doc, Sanis Health
Irbesartan, Hydrochlorothiazide - Mylan, Sandoz, Teva, Zydus Pharmaceuticals
Irovel H - Sun Pharmaceutical Industries, Sin Byu Gyun Trading
Irtan Plus - Ikapharmindo Putramas
Karvezide - Bristol-Myers Squibb, Lek, Sanofi
Sandoz Irbesartan HCT - Sandoz
Velapro Plus - Teva
Other medicines used in combinations with irbesartan and hydrochlorothiazide:
Amlodipine
References and external sources:
Irbesartan main article on Wikipedia: https://en.wikipedia.org/wiki/Irbesartan
Hydrochlorothiazide main article on Wikipedia: https://en.wikipedia.org/wiki/Hydrochlorothiazide
Hydrochlorothiazide, Irbesartan compound on PubChem: https://pubchem.ncbi.nlm.nih.gov/compound/9831761
Irbesartan medication on DrugBank: https://go.drugbank.com/drugs/DB01029
Hydrochlorothiazide medicine on DrugBank: https://go.drugbank.com/drugs/DB00999
Irbesartan FAQ on MedlinePlus (revised 01/15/2018): https://medlineplus.gov/druginfo/meds/a698009.html
Hydrochlorothiazide FAQ on MedlinePlus (revised 02/15/2021): https://medlineplus.gov/druginfo/meds/a682571.html
AvKARE Irbesartan and Hydrochlorothiazide tablets film-coated drug label on DailyMed (revised 09/2022): https://dailymed.nlm.nih.gov/dailymed/drugInfo...
Avalide (Irbesartan and Hydrochlorothiazide) tablets film-coated drug label on DailyMed (revised August 11, 2025): https://dailymed.nlm.nih.gov/dailymed/lookup...
Avalide (Irbesartan and Hydrochlorothiazide) 150/12.5 mg, 300/12.5 mg tablets for oral use official prescribing and patient counseling information from the U.S. FDA (revised 12/2020): https://www.accessdata.fda.gov/drugsatfda_docs/label...
Avalide (Hydrochlorothiazide and Irbesartan) tablets prescribing information from Sanofi pharmaceutical company (revised 08/2025): https://products.sanofi.us/avalide/avalide.pdf
Avapro (Hydrochlorothiazide) and Avalide (Irbesartan, Hydrochlorothiazide) official website powered by Sanofi (revised June 2021): https://www.avapro.com/
Avapro HCT (Irbesartan, Hydrochlorothiazide) tablets consumer medicine information from NPS MedicineWise (revised June 2025): https://www.nps.org.au/assets/medicines/...
CoAprovel (Irbesartan, Hydrochlorothiazide) tablets product information and package leaflet for patients from European Medicines Agency: https://www.ema.europa.eu/en/documents/...
Irbesartan/HCT Sandoz tablets product information from The Therapeutic Goods Administration (revised 29/07/2025): https://www.ebs.tga.gov.au/ebs/picmi/...
Irbesartan Hctz Micro Labs tablets product information from The Therapeutic Goods Administration (revised 30/11/2021): https://www.ebs.tga.gov.au/ebs/picmi/...
Karvezide (Irbesartan & Hydrochlorothiazide) tablets consumer medicine information from NPS MedicineWise (revised June 2025): https://www.nps.org.au/assets/medicines/...
CoAprovel (Irbesartan, Hydrochlorothiazide) 150 mg / 12.5 mg film-coated tablets package information leaflet for patients on Medicines.org.uk (revised January 2025): https://www.medicines.org.uk/emc/files/pil.4112.pdf
Revised: October 2025
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