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Product Name: Eplerenone
Generic Name: Eplerenone
Common Brands: Inspra
Pharmaceutical Categories: Cardio, Blood Pressure, Cholesterol
Where to buy Eplerenone online:
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Eplerenone (trade names include Inspra, Aldactone-EP, Eplenocard, Eptus, Exinia, Inspra-IC, Nonpres, Oldren, Planep, Selara, Suficard) is potassium-sparing diuretic ("water tablets" or "water pills") medication from aldosterone antagonists pharmacological group. This medicine is used for the treatment of high blood pressure (hypertension), congestive heart failure, chronic heart failure, left ventricular dysfunction after a heart attack, central serous retinopathy (central serous chorioretinopathy), patients with resistant hypertension due to elevated aldosterone. It reduces cardiovascular risk in people following myocardial infarction. Eplerenone works as aldosterone antagonists by blocking actions of the hormone aldosterone in the body.
Related medications:
Amiloride (Midamor)
Amlodipine (Norvasc)
Atenolol (Tenormin)
Canrenone (Phanurane)
Diltiazem (Cardizem)
Enalapril (Vasotec)
Hydrochlorothiazide (Microzide)
Irbesartan (Avapro)
Losartan (Cozaar)
Metoprolol (Lopressor, Toprol-XL)
Nifedipine (Adalat)
Olmesartan (Benicar)
Potassium Canrenoate (Soludactone)
Propranolol (Inderal)
Ramipril (Altace)
Spironolactone (Aldactone)
Tasosartan (Verdia)
Telmisartan (Micardis)
Tolvaptan (Samsca)
Valsartan (Diovan)
Verapamil (Calan)
Pharmaceutical and medical classifications:
Aldosterone receptor antagonists
Antihypertensive drugs
Cardiovascular medicines
Diuretics (water tablets)
Medications for the treatment of heart failure
Potassium-sparing diuretics
Selective aldosterone receptor antagonists (SARA)
Spirolactones
Steroidal antimineralocorticoids
Water pills
The Anatomical Therapeutic Chemical (ATC) classification system (developed by the World Health Organization):
C - Cardiovascular system
C03 - Diuretics
C03D - Potassium-sparing agents
C03DA - Aldosterone antagonists
C03DA04 - Eplerenone
Medical conditions for eplerenone in the International Statistical Classification of Diseases and Related Health Problems (ICD):
Other retinal disorders - H35
Central serous chorioretinopathy - H35.71
Essential (primary) hypertension - I10
Heart failure - I50
Left ventricular failure, unspecified - I50.1
Systolic (congestive) heart failure - I50.2
Heart failure, unspecified - I50.9
Chronic systolic (congestive) heart failure - I50.22
Pregnancy category:
B3 - Australia
B - United States (No evidence of risk in humans)
Forms of active pharmaceutical ingredients (APIs):
Eplerenone Base
Chemical, international, and other names of this drug:
Eplerenon
Eplerenona
Eplerenoni
Eplerenonum
Epoxymexrenone
Most known trade names (brands and generics) worldwide:
Aldactone-EP - Pfizer
Diuron - Pliva
Elecor - Almirall
Eplecard - Cadila Pharmaceuticals
Eplenocard - PharmaSwiss
Eplerenon - Accord Healthcare, Actavis, Generics UK, Mylan, Pfizer, Ratiopharm, Stada, Teva
Eplerenona - Actavis, Cinfa Laboratorios, Kern Pharma, Liconsa Laboratorios, Normon Laboratorios
Eplerenone - Actavis, Apotex, Arrow Generiques, Sandoz, Teva, Zentiva
Eplerona - Gador
Eptus - Glenmark Pharmaceuticals, Zoltan Care
Espiro - Polpharma
Exinia - RPG Life Sciences
Inspra - Pfizer, DCH Auriga, Euro Registratie, Fareva Amboise, G.D. Searle, Lexon UK, LF Asia Distribution, LTT Pharma, NPIL Pharmaceuticals, O.P.D. Laboratories, Zuellig Pharma
Inspra-IC - Pfizer
Licepler - Alvogen
Nonpres - Polfa Warszawa
Oldren - Roemmers Laboratorios
Planep - Lupin, Pinnacle CVS
Selara - Pfizer
Suficard - IVAX
Other medicines used in combinations with eplerenone:
Torsemide
References and external sources:
Eplerenone main article on Wikipedia: https://en.wikipedia.org/wiki/Eplerenone
Eplerenone compound on PubChem: https://pubchem.ncbi.nlm.nih.gov/compound/443872
Eplerenone medicine on DrugBank: https://go.drugbank.com/drugs/DB00700
Eplerenone FAQ on MedlinePlus (revised 02/15/2016): https://medlineplus.gov/druginfo/meds/a603004.html
Inspra (Eplerenone) tablets film-coated drug label on DailyMed (revised October 1, 2021): https://dailymed.nlm.nih.gov/dailymed/lookup...
Eon Labs Eplerenone tablets drug label on DailyMed (revised September 10, 2020): https://dailymed.nlm.nih.gov/dailymed/drugInfo...
Inspra (Eplerenone) 25 mg, 50 mg tablets for oral use official prescribing information and medication guide from the U.S. FDA (revised 05/2018): https://www.accessdata.fda.gov/drugsatfda_docs/label...
Inspra (Eplerenone) film-coated tablets prescribing information from Pfizer pharmaceutical company (revised 08/2020): http://labeling.pfizer.com/showlabeling.aspx?id=599
Inspra (Eplerenone) tablets 25 mg and 50 mg product monograph and consumer information from Drug and Health Product Register (revised January 19, 2017): https://pdf.hres.ca/dpd_pm/00041000.PDF
Inspra (Eplerenone) product information on Pfizer Inc. website: https://www.pfizer.com/products/product-detail/inspra
Inspra (Eplerenone) tablets consumer medicine information from MedSafe (revised August 2021): https://medsafe.govt.nz/Consumers/cmi/i/inspra.pdf
Inspra (Eplerenone) 25 mg, 50 mg film-coated tablets package information leaflet for users from Medicines.org.uk (revised 03/2024): https://www.medicines.org.uk/emc/files/pil.120.pdf
Revised: March 2024
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